Acute Intermittent Porphyria: A Review and Rehabilitation Perspective

Acute intermittent porphyria (AIP) is an uncommon metabolic disease that impacts multiple organs and can manifest in many ways. It often misdiagnosed due to its nonspecific symptoms. Neurovisceral signs symptoms should alert physicians consider AIP the differential after excluding more common causes. Identifying underlying cause critical preventing acute attacks, trigger avoidance optimal approach managing AIP. Medications are contraindicated be reviewed thoroughly. Prompt intravenous hematin administration primary treatment for additional pharmacological therapies may necessary treat concurrent A severe neurological manifestation of flaccid paralysis or motor weakness, which develop into total quadriplegia respiratory insufficiency. comprehensive rehabilitation program integral aspect plan. Since incidence this low, functional prognosis not well-known. As a result, it challenging determine most appropriate structure, intensity, duration therapy. By extending plan, individuals with tetraplegia continue make gains years onset weakness. Understanding disease’s will aid coordinating resources improving healthcare expenditures.